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Management Forum

Pre-Filled Syringes: End-to-End Processing Training Course

Topics such as quality of syringe manufacture, quality of syringe components and why, quality of filling (volume check, reject reduction), quality of inspection and product release will be discussed in detail.

★★★★★ "It was an enlightening course, and the speakers were so explanatory."

20-21 March 2025
+ 21-22 July 2025, 5-6 November 2025 »

from £1299

Need help?  Enrol/reserve

Course overview

This intensive two-day course has been designed to offer a comprehensive, practical, and usable review of the production of PFS and will provide the latest information on all aspects of the process from manufacture and packaging for fill/finish through to final (post-fill) inspection. Quality will be a key focus of the programme and there will be extensive coverage of improvements in the manufacturing process, including advances in cleanroom technology and sterilisation. Other sessions will address visual inspection and the latest regulatory requirements to ensure that you are fully up to date. The faculty of speakers will provide key guidance and advice from their practical experience in this field and there will be ample opportunity for discussion.

This course is of our range of Medical Devices training courses - now also including Medical Devices Cyber Security training to help improve your data security.

Benefits of attending

  • Explore recent improvements in the manufacturing process
  • Understand visual inspection
  • Know the latest regulatory requirements

Who should attend?

This event is ideal for pharma start-ups, small and medium-sized pharma companies, CROs, CMOs, machine suppliers, hospital dispensaries, and anyone new to PFS or wanting to learn more in a relaxed and open environment. It will be of value to those working in the area of PFS with responsibility for device programmes, product development, product life cycle management, regulatory affairs, quality assurance and combination products. Drug delivery specialists, business development managers and product development managers will also find this course beneficial.

Enrol/reserve

This course will cover:

Syringe manufacture from components to the final product – an overview

  • The initial choice – bulk or pre-sterilised components?
  • Siliconisation – not beloved, but required
  • Handling and process overview

Filling and closing: Introduction to PFS Filling & Closing Machines with Examples

  • The Basics
  • PFS Dosing Systems
  • PFS Closing Methods
  • Multi-Format Machinery (PFS, Cartridges, Vials)

Overview: Trends in PFS: Machine Technology

  • Pumps ‘fit for purpose’
  • In Process Control (IPC), filling & stoppering
  • Containment
  • Use of Robotics

Terminal sterilisation of pre-filled syringes – strange but feasible

  • Why
  • How it is done
  • Points to consider
  • Validation

Visual inspection of pre-filled syringes

  • Defects and their detection
  • Inspection Methods
  • Assessing Batch and Sorting Quality
  • Specific Aspects of pre-filled Syringes
  • Visual Inspection in the Quality Life-Cycle
  • Setting up a manual Visual Inspection

Secondary packaging machines for PFS: An Introduction

  • What is Secondary Packaging?
  • Walk through a typical facility 2° packaging line (example/video)
  • Trends in Secondary Packaging
  • PFS handling special: Glass-to-glass contact

Overview: Trends in PFS: Drug Delivery

  • Market Dynamics
  • Innovation in PFS
  • Drug Development Trends
  • Manufacturing

PFS from the early days to the latest developments

  • Evolution of systems
  • Evolution of components
  • Evolution of application and application systems

Device Assembling and Control Processes for Auto Injectors

  • Target Product Process
  • Impact Primary packaging material
  • Assembling steps
  • Inline Controls
  • Function / Release Tests
  • Final Packaging

A Primer on System Selection

  • Points to consider
  • Available options

Regulatory requirements for pre-filled syringes

  • ISO design compliance
  • New MDR – what about it?
  • US requirements for combination products

Case study/workshop

Based on the key user requirements provided, participants will come up with outputs for:

  • Design features of the PFS
  • Test methods
  • Manufacturing processes and manufacturing environment

PFS state-of-the-union address and event summary

  • Review of the Market for PFS
  • Review of PFS Processing
  • Future trends in PFS

Enrol/reserve

Dale Charlton
DCBio Automation SIA

Dale Charlton is a Freelance Consultant for automation and fill / finish. Dale has spent a lifelong career in Life Sciences and Biotechnology encompassing both the academic and industrial sectors. Dale worked in a technical capacity in basic R&D at a major University and EMBL Heidelberg before embarking on a more formal academic career in biotechnology and studying for a PhD within the Drug Discovery Group of Pfizer into growth factor research (rGH, GHRF, IgF) . With industrial spells at Porton Down and Pittman-Moore (formerly Glaxo Animal Vaccines) in API and API scale-up, Dale settled back into biotech manufacture and moved more into the supply chain of finished drug products for small molecules & biologics, first as the MD of a life sciences distribution company and later as Director of Business Development, Optima pharma in sterile production automation. Having worked in the pharmaceutical industry from R&D to finished drug product, Dale has a unique understanding of the entire drug development life cycle and offers insight from both the pharma and a suppliers perspective.

More details

Andreas Rothmund
Vetter-Pharma

Dr. Andreas Rothmund is Qualified Person (retd) at Vetter Pharma-Fertigung in Ravensburg, Germany, an independent contract manufacturer specialised in the aseptic production of pre-filled application systems. He started his industrial career in 1985 as a lab manager. After two years he took over production responsibility for a German company specialised in eye drops and eye ointments, a position he held for nearly eight years.

He joined Vetter in 1994, where he has held several positions, including Head of Production for one of Vetter’s aseptic production units. He holds a degree in organic chemistry from the University of Constance, Germany.

More details

Susanne Hall
Vetter Pharma

More details

NEW higher discounts for multiple bookings - bring your colleagues to make your training budget go further:

  • 30% off the 2nd delegate*
  • 40% off the 3rd delegate*
  • 50% off the 4th delegate*

Please contact us for pricing if you are interested in booking 5 or more delegates

20-21 March 2025

Live online

09:30-17:00 UK (London) (UTC+00)
10:30-18:00 Paris (UTC+01)
05:30-13:00 New York (UTC-04)
Timings may be different for each day
Course code 14610

  • GBP 1,299 1,499
  • EUR 1,819 2,099
  • USD 2,087 2,399

Until 13 Feb

View basket 

 
Not ready to book yet?

for 7 days, no obligation

21-22 July 2025

Live online

09:30-17:00 UK (London) (UTC+01)
10:30-18:00 Paris (UTC+02)
04:30-12:00 New York (UTC-04)
Timings may be different for each day
Course code 14876

  • GBP 1,299 1,499
  • EUR 1,819 2,099
  • USD 2,087 2,399

Until 16 Jun

View basket 

 
Not ready to book yet?

for 7 days, no obligation

5-6 November 2025

Live online

09:30-17:00 UK (London) (UTC+00)
10:30-18:00 Paris (UTC+01)
04:30-12:00 New York (UTC-05)
Timings may be different for each day
Course code 15045

  • GBP 1,299 1,499
  • EUR 1,819 2,099
  • USD 2,087 2,399

Until 01 Oct

View basket 

 
Not ready to book yet?

for 7 days, no obligation

* Early booking discounts may not be combined with other discounts or offers. As such, the discounts for 2nd/3rd/4th delegates are based on the full price; and apply only when booking multiple delegates on the same date.

Reviews of IPI's Pre-Filled Syringes: End-to-End Processing training course


It was an enlightening course, and the speakers were so explanatory.

Nov 6 2024

Stergios Kemidis
Head of R&D, ANFARM HELLAS S.A.

Nov 6 2024

Speakers were very knowledgeable and openly shared their experience with the audience especially when asked about specific examples.

Natalia Harasimiuk
Associate Director, Fuji Film

Mar 30 2023

I enjoyed it. I came to the webinar knowing nothing about the process, and I got away with a lot of knowledge. I enjoyed the chat between Andreas and Dale during the presentation, sharing their experience and complementing each other, that was knowledge beyond videos and presentations.

Serge Batubenge
Mgr. Engineering , Regeneron Pharmaceuticals, Inc.

Mar 30 2022

It was very good, I was impressed, I would have loved to do this course in person but this was a good alternative. The speakers were very good, very knowledgeable but also good at teaching/ relating information. The presentations were easy to follow, it was useful to have the documents there to follow along as the speakers talked. All the content was relevant to the topic and occasional humus. I enjoyed the course and would recommend Management Forum to my colleagues.

Zhané Healey
Senior Laboratory Technician, Medical Engineering Technologies

Mar 27 2019

Very knowledgeable and helped answer numerous questions. Very helpful and interested in individual challenges.

Gabrielle Kelsey
Production Manager, Torbay Pharmaceuticals

Mar 20 2017

Very informative, good overview of PFS development. Speakers were knowledgeable.

William Turner
Associate Bioedical Engineer, Meridian Medical Technologies, a Pfizer Company

Mar 20 2017

Friendly, knowledgeable people. I would have liked to go a bit deeper into the technical parts (syringes, tubs, machines)

Marc van Nispen
Project Engineer, EMCM B.V.

United Kingdom

  • 3P Innovation Ltd
  • 42 Technology Ltd
  • Almac Group
  • Archimedes Pharma Ltd
  • Astech Projects Limited
  • ASTECH PROJECTS LTD
  • AstraZeneca
  • Becton Dickinson UK Ltd (Oxford)
  • Bespak Europe Ltd
  • Calea UK Ltd
  • Cambridge Design Partnership
  • Cardinal Health
  • Catalent Pharma Solutions
  • Ethypharm
  • Fuji Film
  • Future Injection Technologies Limited
  • GlaxoSmithKline
  • Glide Pharmaceutical Technologies Limited
  • Harro Hoefliger Packaging Systems Ltd
  • IT Pharma
  • Martindale Pharma
  • Medical Engineering Technologies
  • Medicines and Healthcare Products Regulatory Agency (MHRA)
  • OnDrugDelivery Ltd
  • Oval Medical Technologies Ltd
  • Owen Mumford Ltd
  • QRC Consultants Ltd
  • Salvus Technology Limited
  • Sanofi-Aventis
  • Team Consulting Ltd
  • Technology Partnership Plc
  • Terry Weston
  • Teva Pharmaceuticals Europe B.V.
  • Tip-top.com Limited
  • Torbay Pharmaceuticals
  • Torbay Pharmaceuticals Ltd
  • UCB Celltech
  • ViiV Healthcare
  • West Pharmaceutical Services
  • West Pharmaceutical Services Cornwall Ltd
  • Wyeth Pharmaceuticals

Germany

  • Abbott Products GmbH
  • B Braun Melsungen AG
  • Bayer Pharma AG
  • Gerresheimer Bunde GmbH
  • Medac GmbH
  • Nipro Glass Germany AG
  • Optima Group pharma
  • Rexam Pharma GmbH
  • Robert Bosch GmbH
  • RPC Formatec GmbH
  • Sanofi-Aventis Deutschland GmbH
  • Schott AG
  • Schreiner Group GmbH & Co KG
  • Vetter Pharma International GmbH

United States of America

  • Abbott Laboratories
  • Advanced Electron Beams
  • Alexion Pharmaceuticals Inc
  • AMGEN INC
  • BD
  • Eli Lilly and Company
  • Genetech Inc
  • IDEO
  • Meridian Medical Technologies Inc
  • Meridian Medical Technologies, a Pfizer Company
  • NA
  • Portal Instruments
  • Regeneron Pharmaceuticals, Inc.
  • West Pharmaceutical Services Inc.

Switzerland

  • Actelion Pharmaceutical Ltd
  • Bioeq AG
  • CSL Behring AG
  • F. Hoffmann-La Roche Ltd
  • Forteq Healthcare
  • Geistlich Pharma AG
  • Haselmeier GmbH
  • Komax Systems LCF SA
  • Merck
  • Mikron SA Boudry
  • Novartis Pharma AG
  • Schott Schweiz AG
  • Ypsomed AG

France

  • Aptar Pharma
  • BD Medical – Pharmaceutical Systems
  • Becton Dickinson
  • BIOCORP
  • Cabinet Michel Richebourg
  • Guerbet
  • Linac Technologies
  • RUMPLER TECHNOLOGIES
  • Stelmi SA

Netherlands

  • Amgen Europe BV
  • Bilthoven Biologicals BV
  • EMCM B.V.
  • Interdos Pharma B.V.
  • MSD B.V.
  • MSD/NV Organon
  • Sever Pharma Solutions
  • Synthon Biopharmaceuticals BV

Israel

  • Elcam Medical Ltd
  • Flextronics Design srl
  • Sindolor Medical Ltd
  • Teva Pharmaceutical Industry Limited
  • Teva Pharmaceuticals Industries Ltd
  • West-Medimop

Sweden

  • Apotek Produktion & Laboratorier AB
  • Apoteket Produktion & Laboratorier AB
  • BD Medical - Pharmaceutical Systems
  • BECTON DICKINSON AB
  • Q-Med AB
  • UPPSALA UNIVERSITY HOSPITAL

Austria

  • Baxter Innovations GmbH
  • BD Medical - Pharmaceutical Systems
  • EBEWE Pharma
  • Sandoz GmbH
  • Takeda Austria GmbH

Denmark

  • ALK-Abello A/S
  • Bang & Olufsen Medicom AS
  • Ferring Pharmaceuticals A/S
  • LEO Pharma
  • Novo Nordisk A/S

Italy

  • Alfa Wassermann S.p.A
  • Chiesi Farmceutici S.p.A.
  • Nuova Ompi srl
  • Sinclair Pharma SRL
  • TÜV Rheinland Italia S.r.l.

Belgium

  • Baxter R&D Europe
  • Datwyler Pharma Packaging Belgium NV
  • Glaxo Smithkline Biologicals
  • Toxikon Europe NV

Ireland

  • BioMarin
  • Crospon Limited
  • ENTERPRISE IRELAND
  • Tech Group Europe

Finland

  • DelSiTech Ltd
  • Phillips-Medisize

Croatia

  • Agency for Medicinal Products and Medical Devices of Croatia (HALMED)

Greece

  • ANFARM HELLAS S.A.

Hungary

  • Gedeon Richter Plc.

India

  • Piramal Healthcare Limited

Japan

  • Daicel Corporation

Latvia

  • DCBio Automation SIA

Spain

  • Admiral S.A.

Enrol/reserve

Run Pre-Filled Syringes: End-to-End Processing Live online for your team

2 days

Typical duration

Pricing from:

  • GBP 800
  • Per attendee, based on 10 attendees
  • Course tailored to your requirements
  • At your choice of location, or online

 

We can customise this course to your requirements and deliver it on an in-house basis for any number of your staff or colleagues.

Contact our in-house training experts Aleksandra Beer and Yesim Nurko to discuss your requirements:

Multiple colleagues? See above for details of our discounts for 2, 3, or 4 delegates. For more, talk to one of our training experts to discuss how to:

Run this course conveniently and cost-effectively in-house for your staff and colleagues

Aleksandra Beer

Aleksandra BEER
Training expert

Yesim Nurko

Yesim NURKO
Training expert

+44 (0)20 7749 4749

inhouse@ipi.academy